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Оглавление - All about Genomics
Unlock the secrets of your DNA and discover the power of genomics
- 1. Introduction to Genomics: What it is and Why it Matters
- 1.1 What is Genomics?
- 1.2 The Significance of Genomics
- 1.3 The Promise of Genomics
- 1.4 Overview of the Book
- 2. Understanding DNA: The Building Blocks of Genomics
- 1. Introduction to DNA: What it is and Why it Matters
- 2. DNA Replication: Copying the Genetic Code
- 3. DNA Sequencing: Reading the Genetic Code
- 4. DNA Mutations: Altering the Genetic Code
- 5. Epigenetics: DNA Modification without Changing the Code
- 6. Genome Evolution: Tracing the History of Life
- 7. Conclusion: Implications of DNA Understanding in Genomics
- 3. The Human Genome Project: A Brief History
- — Introduction to the Human Genome Project (HGP)
- — Brief history of the HGP, including its origins, goals, and timeline
- — Key individuals and organizations involved in the HGP
- — Major milestones and accomplishments of the HGP
- — Ethical, legal, and social implications (ELSI) of the HGP
- — Impacts of the HGP on scientific research and medicine
- — Criticisms and limitations of the HGP
- — Current and future directions of genomic research in light of the HGP
- 4. Genomic Technologies: Sequencing, Editing, and Analysis
- — Next-generation sequencing (NGS) technologies, including Illumina, Ion Torrent, and Pacific Biosciences
- — Third-generation sequencing technologies, including Oxford Nanopore and PacBio
- — Single-cell sequencing technologies, including droplet-based methods and single-cell ATAC-seq
- — Genome editing technologies, including CRISPR-Cas9, TALENs, and ZFNs
- — Bioinformatics tools and databases used in genomics research, including NCBI and Ensembl
- 5. Genomic Data: Ethics, Privacy, and Regulation
- 6. Genomics and Personalized Medicine: From Diagnosis to Treatment
- — The concept of personalized medicine and its relationship with genomics
- — Applications of genomics in personalized medicine, including disease risk assessment, diagnosis, and treatment
- — Case studies of personalized medicine in cancer, cardiovascular disease, and rare genetic disorders
- — Challenges and limitations of personalized medicine
- — Ethical considerations in personalized medicine, including privacy, informed consent, and access to care
- — Future directions in the field of genomics and personalized medicine
- 7. Applications of Genomics: Agriculture, Conservation, and Biotechnology
- 8. Genomics and Society: Impacts and Future Directions
- 9. Frequently Asked Questions: Answers to Common Queries About Genomics
- 10. Glossary of Genomic Terms